Recently Cancer Treatment Centres of America (CTCA) and Nanospectra Biosciences have announced that the Gold nanoshells invented at RICE have been planned to go for trial in Lung Cancer therapy. Nanospectra has already come up with Aurolase therapy, which uses heat to destroy cancer cells.
The technology is useful and also protects the healthy tissues as the nanoparticles in this case are encased inside the thin gold shell and these are absorbed by tumors. Scientists at RICE behind the research are extremely happy to see that Cancer Treatment Centre of America has come forward and will conduct trial on this unique technology.
RICE has done some extraordinary research on nanoshells and nanoparticles and has published a number of papers in various national and international journals. The present clinical trial to be conducted by Nanospectra and CTCA has not only been approved by CTCA Institutional Review Board but has also been approved by Food and Drug Administration. The clinical trial will be conducted by Dr. Mark Lund and other colleagues in Interventional Pulmonology Department and it will involve treating primary and metastatic lung cancer.
Material Scientists globally are working to improve the performance of batteries and now Materials Scientists have developed a new light weight colloidal film based electrode for lithium-ion batteries. The new technique will open new possibilities for reducing the weight and volume of lithium-ion batteries.
The research paper findings have been published in the October 10th issue of Nano Letters. Nanoparticles can significantly enhance the electrochemical properties of the batteries and therefore these have been investigated for their suitability as electrodes in the lithium-ion batteries.
For using colloidal nanoparticles as lithium ion battery electrodes, these has to be combined with the carbon-based conductive materials that can enhance the charge transport and at the same times, these also needs to be combined with the polymeric binders so that the nanoparticles are together to make an electrode substrate. For depositing the nanoparticles to the surface of electrode substrate, researchers used electrophoretic deposition technique.
With the technique, researchers were able to make significant improvement in the battery electrode and using the electrophoretic deposition a superior film that possesses excellent mechanical stability was formed.
Seashell Technology, an industry leader in silver nanowire, has recently announced two new products AgNW-25 and AgNW-130 and will showcase these products at the IDTechEx conference at Santa Clara, California in December 5th & 6th 2012. These nanowires will have an average distribution size of 25 nm and 130 nm respectively.
Seashell produces silver nanowires using HiFlex eFilmTM technology and these silver nanowires possess excellent electrical and thermal conductivity and at the same time Seashell Technology is also known for some of its breakthrough in multiple fields. Products made by the company including transparent conductors, flexible and stretchable conductors, conductive fillers are being widely used worldwide.
These new nanowires AgNW-25 and AgNW-130 are designed to have 20nm and 30 nm length and having high aspect ratio, these silver nanowires and especially AgNW-25 possesses enhanced electrical and thermal properties and therefore can find applications in many applications including transparent conductive films. Similarly AgNW-130 can find applications where high conductive materials are required.
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Biologists always look for behaviors of cells and now researchers at UCLA Henry Samuel School of Engineering and Applied Science have found a new tool that can help in manipulating how thousands of cells divide and develop structures and this new tool will be helpful in many areas of medical science.
The research findings have been published recently in the journal of Nature Methods and so far the understanding the complex behavior of cell was challenging due to non-availability of sufficient resolution tools. To cater with the problem of finding high resolution tools that can provide accurate and meaningful information inside the miniature environment of a cell, an interdisciplinary team of researchers from ULCA was formed.
The researchers developed a platform where by manipulating magnetic nanoparticles, they produced local mechanical signals and received different responses from within the cells. Further same shape of nanoparticles were used and researchers were able to get responses from thousands of cells. The study resulted in fruitful results and the research was funded by NIH’s new innovator award.
Colors and especially the bright colors are the result of the object’s property to reflect light and now the researchers at the University of Pennsylvania has generated structural colors. These structural colors resemble super – hydrophobicity, the unique ability of butterfly wings.
The research was published in the journal Advance Functional Materials and as per the research findings, researchers used a non-conventional lithography technique known as holographic lithography. The research team aimed at providing structural colors and hydrophobicity by providing periodic pattern and surface roughness.
The researchers used a material called phoresist and created a crossed linked 3D network and the photoresist material was later removed by solvent. The researchers later found holes in the 3D lattice and by changing solvents after washing away the photoresist material, the research team were able to provide the sufficient roughness to the 3D structure.
Energy is essentially required for developing as well as developed countries and due to limited non-renewable resources, alternate sources for producing clean energy are being looked for and researchers all across the globe are working on fuel cells. The major hurdles for producing energy from fuel cells are the cost and efforts are being to minimize the energy production cost.
Researchers at Umea University in Sweden have recently published their findings in ACS Nano where the team provides the key processes in producing the catalysts. Fuel cells are based on hydrogen and oxygen and for converting chemical energy into electrical energy; various forms of catalysts are used.
The major problems with these catalysts are that currently these catalysts are very costly as these are made from extremely expensive noble metals containing platinum, ruthenium and other metals. A research report has already found that the organic catalyst based on nitrogen-doped carbon nanotubes could be useful in catalyzing oxygen and now researchers deliberately created defects in carbon nanotubes and by replacing some carbon nanotubes with nitrogen atoms.
These especially designed carbon naotubes thus have increased electron density around local centres and thus the increased electron density leads to the desired catalytic properties. Researchers found that the catalytic effects are much higher around certain deliberately created nitrogen defects. Researchers could also increase the inefficient catalytic effects of nitrogen defects by heating and thus the finding can help in developing future fuel cells.
Optical bioimaging is emerging very fast and it is one of the promising tools being explored in the biomedical applications, however current technologies limit the ability to look deeper inside. Due to non-availability of high resolution and high contract imaging tools, a group of international researchers and scientists worked together for developing a robust and high resolution optical device that can help them in identifying tumors.
The group of researchers has created a unique photoluminescent nanoparticles that are able to pass light through a depth of more than 3 centimeters and actually these nanoparticles are inside a shell of calcium fluoride and the nanocrystalline core contains thulium, sodium, fluorine and ytterbium. The use of calcium fluoride shell minimizes the possible side effects as it is commonly found in our bones.
These nanoparticles as mentioned above have different behavior towards light, as these nanoparticles absorb infrared light and emit infrared light of lower wavelength than the absorbed light and this is completely deferent than the normal pattern of absorbing and emitting lights of biological tissues and therefore these nanoparticles can suitably be used for obtaining deeper and higher contrast images.
The research paper has been published on 28th August in the online issue of ACS Nano Journal. The research teams of various institutes and research centre from US, China, South Korea and Sweden have worked together. Distinguished Scientists Paras N Prasad, Professor and Executive Director, UB’s Institute of Lasers, Photonics and Biophotonics & Gang Han, Assistant Professor, University of Massachusetts Medical College has jointly led this research study.
Fuel Cells are being tried in new generation vehicles and these vehicles will run on hydrogen, however this technology is lacking due to one great problem of hydrogen storage and researchers across the globe are looking for new storage devices so that the hydrogen cell vehicles are made commercially viable.
Hydrogen, a very low density gas is one of the most efficient and environmental friendly fuel as it exhausts only water, however the present technique available for storing it can not allow to store it in sufficient quantity. A new material is synthesized by reacting hydrogen with carbon nano-structured material by a research scholar at Umea University. In the doctoral study, Serhiy Luzan studies various metal organic frameworks MOFs, and their advantages.
Luzan reacted fullerene C60 with the hydrogen in various conditions such as at high temperature, at high pressure, with and without metal catalysts and the reaction resulted in formation of hydrogenated fullerenes. This complex structure of hydrogen fullerene upon excess treatment with hydrogen broke down into smaller structures, which was earlier difficult to produce. These structures were stabilized with hydrogen and thus were accommodating higher amount of hydrogen and further research used relatively in expensive material.
Cellulose acetate nanofilter membranes have been modified by Iranian researchers in such a way so that these membranes can separate nitro-aromatic poisons from water. The research findings has been published in the Journal Desalination of 30th March 2012.
Nanofiltration is one of the emerging techniques that is being use for separating pollutants from waste water or polluted water so that the water can be reused. The technique has higher efficiency, low cost and at the same time does not require chemical compounds and other complex ingredients.
Cellulose acetate polymers have numerous advantages such as resistance against solvents, low cost, high affinity and due to these advantages, these polymers are the suitable options for synthesizing nanofilter membranes, however the synthesized membranes have some disadvantages also including the surface layer of the membrane with high thickness. This relatively dense membrane reduces the overall performance of the nanofilter membrane.
Researchers have added sodium dodecyl sulfate, an ianionic surfactant as an additive to improve the structural properties of synthesized nanofilter and studies the two important parameters flux and percentage of the poison permeation under different environmental conditions. The most common pesticides reported by USEPA Nitrophenols; p-nitrophenol (PNP) and 3,5-dinitrosalicylic acid (DNSA) were selected for the present study and the various parameters were collected and reported.
Nanoparticles now a days are being used fr multiple applications and synthesis of various nanoparticles in desired range is one of the complex task and researchers across the globe are finding ways to develop easy and efficient techniques of synthesis. Researchers at University of Isfahan have recently reported a new synthesis method in the Journal of Catalysis.
The researchers claim that the new method of synthesis will enable the researchers to synthesize platinum cobalt nanoparticle that will have lower dimensions, narrower size distribution and at the same time will have better stabilities than the nanoparticles synthesized using traditional methods. The research is aimed at the development of advance methanol fuel cells by providing Pt based catalysts.
Pt based catalyst for methanol oxidation reactions are being developed for use in the fuel cells and by suitably choosing a substrate; these can be used for high temperatures. Researchers have designed a method to fabricate a Pt-based alloy on CNT substrate that is highly thermal stable and at the same time have the desired size of 3 nm only. Researchers have selected elemental sulfur as modifying agent and for avoiding the possible catalyst poisoning, they eliminated sulfur through a thermal treatment process.
Cadence Design Systems Inc. has recently announced the DDR4 SDRAM PHY memory controller design that has been proven in the silicon process technologies. Cadence, a global design and innovation company by extending its leadership in DRAM technology, has characterized DDR PHY and controller intellectual property (IP) in 28 nm silicon.
The DDR4 technology is expected to be made available by the end of the year, will have significant performance advantage over the existing DDR3 technology. The DRAM devices that will use DDR4 standard are expected to have 50% higher operational frequency and at the same time, will consume around 40% less power per bit transferred over the device that uses DDR3.
The DDR4 is going to be one of the features in DRAMS and the Cadence silicon-proven PHY family now includes high speed DDR4 PHY that will fulfill the requirements of next generation computing, home entertainment devices, networking, cloud infrastructure etc. Cadence is hopeful that the SoC designers now have multiple options for fast power efficient technologies for next-generation mobile devices.
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Laser micro-machining is one of the technique used for a wide range of precise machining applications and now a new technique has been developed that can produce laser beams with unusual modes of electric field. The new technique is developed by scientists at University of Liverpool and the research findings have been published in the Journal of Optics.
The new technique could find broad ranges of applications and can have major impacts by increasing the process efficiency and use of different modes of polarization or electric fields. The applications such as producing radial and azimuthal polarization modes have been successfully demonstrated by researchers at Liverpool School of Engineering by using Hamamatsu Spatial Light Modulator.
Research team used a 100 femtosecond (fs) pulse laser source & a spatial light modulator with a wave plate for demonstrating the new technique. The new mode of polarization has provided much better quality of processing speed and further the radially polarized team has increased the machining speed due to higher absorption of radial polarization, which increased the coupling of laser energy during machining.
As per a research paper in the journal Applied Physics Letters, Volume 101, Issue 4, published online on 27th July 2012, researchers in US has come out with the detection and sizing of a smallest known virus. The study was conducted jointly by the researchers at Polytechnic Institute of NYU & NYC College of Technology Brooklyn; Fordham University, Bronx, NY and Hunter College of CUNY, NY, USA.
Researchers for obtaining the results have fixed nanoscale gold spheres onto the microscopic heads of glass and thus created a super sensor. This sensor was sensitive enough to provide an enhancement of the order of 70X.
“Whispering gallery mode” is a phenomenon of light observed at the famous circular gallery of St. Paul’s Cathedral, London where even the smallest whisper near the wall can be heard around the gallery and in a similar way, the light waves are sent whirling around the inside of glass bead that resonates at a specific frequency.
By adding the gold nano spheres to the glass beads, researchers were able to magnify the signal 70 times, which earlier was unable to detect smaller viruses with the lone glass spheres. Researchers thus created the plasmonic hot spots as they call the spots created by gold nanospheres and in these spots the light wave coupled electronics waves. The sensor so obtained was not only able to detect the presence of smallest virus but also the precise weight of the virus.
Cancer is one of the deadly diseases and large number of people suffers from various types of cancers across the globe and for effectively treating cancer, some of the cancer treatments now include immune system boosters to enhance the effectiveness of the treatment. According to the new research, the new novel treatment system is developed by researchers at the Yale University.
The research findings led by Tarek Fahmy, have been published in the journal Nature Materials and researchers claim that the combination of anticancer drug and immune booster system have been effective in delaying cancer in mice. The researchers claim that in mice they observed delayed tumor growth, sent tumors into remission, which ultimately increased the survival rates.
The new drug transport technology called nanolipogels (NLGs) was developed by researchers and used two drugs for the study. These drugs were transported through NLGS, nanoscale, hollow and biodegradable spherical structure that can accumulate in tumors and once reaching in these tumors can release controlled dosage of their cargo into the blood stream by breaking down the spherical walls. These NLGs were filled with both inhibitor drug and a protein that works as immune booster.
Food and vegetable waste is one of the increasing problems in various parts of the world, however it can be used for some of the excellent applications. One of such applications is biosynthesis of silver nanoparticles. A recent research study has been published in this regard in the International Journal of Nanoparticles.
According to this research, pomegranates peels can be suitably used for synthesizing silver nanoparticles. Punica Ganatum, is found cultivated in large parts of Mediterranean region and especially in North India and the extract of this fruit is an excellent source of antioxidants.
Naheed Ahmad, Botanist at Patna University and Seema Sharma, Physicist, AN College Patna are jointly working with the pomegranates. Researchers are trying to use the skin of pomegranates as reducing agent for making silver nanoparticles. Presently most of the reducing agents are either chemical reducing agents and the present method is more environmental friendly.
The nanoparticle formation takes place from silver nitrate solution and the reaction proceeds ambient temperature and the nanoparticles generated using pomegranate skin are about 5 nm size. It is suspected that the biological constituents present in the pomegranate acts as reducing agent.
Applied Nanotech Holdings Inc., a global nanotech leader company has recently announced that they have received a contract for $275,642 for developing glass fiber-reinforced composite (GFRP). These glass fiber-reinforced composite panels are useful in improving the protection of facilities from ballistic and blast threats. These are also useful in protecting the important army equipments from electromagnetic interference and seismic events.
The U.S. Army Engineer Research and Development Center’s Construction Engineering Research Laboratory (ERDC-CERL) has earlier awarded two contracts to Applied Nanotech and it is the third contract in line. Applied Nanotech is happy to work on the development of the material for national army and hope that the new material will enhance the protection of various equipment and accessories of the countries defense forces.
Applied Nanotech Holdings is a global technology company that not only solve the problems at nano level but it also focuses on commercialization of the technologies developed by it’s research wing. It has a team of highly skilled scientists and engineer that work with various companies and organizations and the company sell products and license patents.
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A lot of nanomaterials are being used in numerous applications including various products, however the biological and environmental information on these nanomaterials is really important for the user and at the same time the information is either not available or it is scattered. Thanks to RTI International, who have come up with nanomaterialregistry.org, which allows the user to browse the information.
The information at the website is available for free and anyone can search and browse the characteristics data on a number of nanomaterials. This resource is very helpful for individual user of nanomaterials, nanomaterial community and researchers as it provides data that are systematically curated on the minimum information standards.
The registry is sponsored by the National Institute of Health and it is designed to provide the web based information on various nanomaterials to the stakeholders and abilities search as search, query, reporting data with link to the associated publication, tools, manufacturing processes and models have been provided. A lot of data from existing online sources has been gathered and new resources are being added.
X-Ray imaging is one of the common tool used for a number of applications in all fields including medical imaging and now a highly innovative high resolution wafer scale digital image sensor has been developed by the Science and Technology facilities Council’s (SFTC), which could significantly contribute in medical imaging applications. The CMOS Sensor design group at Rutherford Appleton Laboratory (RAL) has used advance analog tools from Tanner EDA.
The new target applications for the new sensor device include the X-Ray imaging particularly used in mammography and digital tomosynthesis , which helps in three dimensional image representing patients or other scanned objects. As the conventional X-ray imaging techniques are now being replaced by modern solid state X-ray detection systems and these new techniques are much superior in imaging and have cost advantage also. However, as CMOS imaging does not use any lens and therefore the sensor image size should match the target area and the sensor size varies for various imaging applications.
The new innovative technology developed by the group have some advantages as it has sensing pixels right up to the edges on the three sides of the images, which allows to use multiple sensors that are manufactured on 200mm silicon wafers and these are also tiled in 2X2 arrangements. This arrangement covers larger imaging area, which is required for some of the medical imaging applications such as mammography applications.
For covering larger area such as chest imaging or even whole body imaging, the system allows to add 2XN sensor arrangements making it possible to cover large imaging areas. The innovative technique a three-sided buttable design uses some innovative electronic circuitry, which is IP protected and designed to maintain high degree of image quality.
TechConnect World Nanotech Conference was held at Santa Clara California during June 18-21, 2012 and Dr. Julia Ljubimova was invited to the conference as speaker. Dr. Julia, Chief Scientific Officer and President, Arrogene Inc. discussed on the latest developments on nano therapeutics.
The TechConnect conference is one of the largest conference that provides opportunity to various researchers, developers, innovators, users and marketers to interact with each other and at the same time it is one of the best multi-disciplinary and multi sector conference. Dr. Julia is one among the best speakers that was invited to deliberate some of the latest developments in various disciplines.
Some of the innovative technologies has already been developed at Cedars – Sinai Medical Centre and are being under exclusive license by Arrogene. The company has done marvelous job by developing the new generation nanomedicine that are capable of targeting cancer cells and thus further stopping the growth of cancer cells and these technologies has discussed in details at the conference.
Researchers at the University of Colorado have used Nanoparticle Tracking Analysis (NTA) for characterization of biological nanoparticles and the work has been carried out at Professor Hang Yin’s group. The Yin research Lab, University of Colorado at Boulder is engaged in the interdisciplinary research studies interfacing Chemistry, Biology and Engineering.
The research group’s main focus is to study structure based drug design and mainly to identify and design peptides and these peptides then can potentially be used for detecting highly curve extracellular vesicles and micro vesicles. The research group is currently also studying these micro vesicles as potential biomarkers for tumor progression and as per the research the study will help in finding the metastasis stage of cancer.
The research team comprising Professor Hang, Leslie-Anne Morton and Jonel Saludes uses NanoSight LM10 system, which is one of the best systems from NanoSight, the leading manufacturer of unique nanoparticle characterization technology. The research findings of the group has recently been published in the Journal of Visualized Experimentation.
United Microelectronics Corporation (UMC) is one of the leading semiconductor foundry globally and it has recently announced that it has got license for the next generation technology that will enable it to develop 20nm CMOS process with FinFET 3D transistors. As per the details, the UMC can use the design kit and FinFET technology to accelerate the availability of the various processes for their customers.
With the availability of new technology from one of the world’s technology leader IBM, UMC is happy and further the position of UMC’s leadership among semiconductor foundry will further improve their strength in introducing leading-edge processes. The technology will significantly enhance the UMC’s strength on next generation customer chip designs.
UMC is providing advance technology and manufacturing services for applications in major IC sectors and this new development will enable it to move further. UMC provides the production of proven 65nm, 45/40nm and a wide range of specialty technologies. The company employees more than fourteen thousands people across the globe.
Prostate cancer is one of the major problems in men and a large number of men above 50 years of age are advised to check PSA annually to diagnose prostate cancer. The treatment options for the prostate cancer are also limited especially if the disease is in advance stage.
Researchers now suggest a new cancer therapy which uses silicon chip dubbed GEDI (Geometrically Enhanced Differential Immunocapture) and the device can actually identify and collect the cancer cells from patient’s bloodstream. Team of researchers from Weill Cornell Medical College, New York and Cornell’s College of Engineering, Ithaca has built the device.
The device captures the high concentration of rare cancer cells, which are specific to metastatic prostate cancer and the technique also helps in identifying the determination of efficacy of the current chemotherapy. The device provides the CTCs (Circulating Tumor Cells) and therefore helps in understanding the biology of metastasis and for developing new treatment and therapies for treating prostate cancer. The research findings have been published in the April issue of the journal PLos One.
Metastasis tells us about the spreading of cancer cells from prostate to other parts of bodies including liver and lung. These cancer cells pass through blood stream and damages the functions of other important organs and metastasis is the major cause of death among prostate cancer patients. The new device will help in identifying the metastasis stage and will also offer suitable treatment for the disease.
Computers work on binary language that is represented by codes of 0s & 1s and memory devices requires large collection of these components that switches between states. Now researchers are working on new generation memory chips that are to be based on new materials and where the atoms can switch between these phases by rearranging themselves.
Before going further, it is necessary to understand the mechanism of phase change and researchers at the University of Pennsylvania have now provided some insights into how the phase change occurs. The research were jointly carried out by Ritesh Agarwal, Associate Professor, Deptt of Materials Science & Engineering, Penn’s School of Engineering and Applied Science , A.T. Charlie Johnson, Professor Department of Physics & Astronomy, School of Arts and Sciences and Ju, Li, Professor of Nuclear Science and Engineering, Massachusetts Institute of Technology and the research findings was published in the Journal Science.
Actually both types of memories i.e. volatile and non-volatile have the limitations and advantages and for volatile memory, the speed is quite fast, however in case of non-volatile memories, the operation speed is quite low and researchers since long are working on a memory device that is non-volatile and has higher speed with scalability.
PCM or phase change materials are ideal for such type of universal memories and are now also being offered commercially. These PCMs have atoms in ordered lattice in the crystalline phase and atomic arrangement becomes disordered in amorphous phase and in these two phases the electrical resistance for current is at different levels and that’s why these are best options for building memory storage devices.
SOLID State Equipment LLC (SSEC), leading manufacturer of single wafer wet processing equipment for Compound Semiconductor and Silicon Semiconductors and it recently joined hands with SEMATECH for 3D interconnect program at University of Albany’s CNSE. Solid State Equipment LLC by joining the program will be part of the development of cost effective and robust processes and metallurgy solutions.
The collaborative Interconnect program at CNSE’s Albany NanoTech will enhance the opportunities for development of leading edge wafer thinning and through-silica-via (TSV) wafer cleaning processes and researchers will specifically utilize the Solid State Equipment LLC’s platforms for silicon etching through various processes including reveal height metrology and wet cleaning.
SEMATECH, an International consortium of leading semiconductor devices, equipments and manufacturers is committed to foster collaboration across the nanoelectronics industry and this collaboration with the SSEC will also accelerate development and commercialization and further the strength of SEMATECH will help in achieving new goals and targets in this evolving area of nanoscience
The Display Industry Awards, the most prestigious awards in the industry, has recently been announced and these awards recognizes some of the innovative and state of the art display products, components and applications that are going to be the backbones of future global display industry. Since 1995, the most distinguished display are being honored through these awards and this year Display week is in progress from 3rd June in Boston and will be over by 8th of June 2012.
Both gold and silver awards in three categories; Display of the Year, Display Application of the Year and Display Component of the Year and this year gold award for Display Components of the Year goes to Nanosys Quantum Dot Enhancement Film.
Nanosys Inc., is an advance material architect and has come out with the innovative display technology. Several high quality nominations were received from around the world and Nanosys has got the award for quantum dot enhancement film at the convention. Quantum dots can emit lights at precise wavelength and also by controlling the output, ideal backlights can be created, which can be used for LCDs.
DNA Nanotechnology a new emerging field where researchers across the globe are working to explore the use of a nanomaterial that builds tiny programmable structures for various applications. Now, one of the research team at Wyss Institute for Biologically Inspired Engineering, Harvard University has come up with a new method for building complex nanostructures using short synthetic strands of DNA.
The research was conducted under the guidance of Dr. Peng Yin, Faculty Member Wyss Institute and Assisstant Professor of Systems Biology, Harvard University and the research findings has been published in the recent issue of the journal Nature.
The specific synthetic strands of DNA known as single stranded tiles (SSTs) can be programmed in such a way so that these assemble themselves in specific shapes. Each SST, a single short strand of DNA interlocks with another tile if it has complementary sequence and if it has no complementary sequence, it will not combine with the other tile. Thus the tile having complementary sequence combines or assembles in predetermined shapes.
Researchers carried out a number of experiments where they have created hundreds of designs including numbers, fonts and even Chinese characters and used hundreds of tiles for single structures of 100 nanometers. Researchers are hopeful to design the SSTs that can have very useful applications in medicine and allied science disciplines and as these are totally synthetic, these can be made biocompatible as well.
A study was conducted on non-human primates indicate no adverse effect of quantum dots and this study open ways to treat the diseases like cancer through nanomedicine. The research findings are published in the online journal Nature Nanotechnology of dated May 20.
The researchers carried out the experimental work on four rhesus monkeys and injected them with cadmium selenide quantum dots and found that the health of the monkeys is normal for the period of 90 days and no abnormalities in major organs were developed during the period. Researchers also found all vital parameters of these monkeys are within normal range and these animals also didn’t lose weight. The visual observations on these animals were also carried out for one more year and no abnormalities were found.
Quantum dots are tiny luminescent particles that glows under different lights and among quantum dots, cadmium selenide are most common and these are not only have potential applications in the area of nanomedicine but can also find applications in other areas including solar cells, light emitting diodes and computers.
The toxicological studies completed at the multiple locations including the University of Buffalo, the Chinese PLA General Hospital, Nanyang Technology University, Singapore and ChangChun University of Science and Technology China, however researchers still believe that more studies needed to establish the harmfulness of the quantum dots.
Single walled carbon nanotubes are among the best nanotubes that find applications in multiple applications and with the public funding by the BMBF, researchers at Fraunhofer IWS Dresden are now able to develop a suitable process for producing single walled carbon nanotubes at mass scale. The diameter of single walled carbon nanotubes produced by the process is between 1 and 1.6 nm.
The process employed here produces a few micrometer long single walled carbon nanometers and carbon nanotubes show excellent metallic conductivity, however the process developed at Fraunhofer IWS Dresden can be designed to get characteristics features. These carbon nanotubes obtained by researchers at Fraunhofer IWS Dresden have very low density defects with hexagonal arrangements within the atoms.
Currently Fraunhofer IWS is one of the premier institute that can produce best quality single walled carbon nanotube and the process is very promising for mass production of carbon nanotubes that can possess excellent electrical, mechanical and mechanical properties. These single walled carbon nanotubes have 1000 times current density and 10 times tensile strength than that of copper.
Ina recent development, researchers at the College of William & Mary have combined polymers with graphene. The addition of graphene to the polymer enhances the functionality of polymers and the new materials can therefore find multiple applications as these are super strong and much more flexible than ordinary plastics.
The research findings have recently published in the journal Macromolecules. According to the researchers, the graphene oxide reinforced polymers being light weight could open up new material possibilities. The light weight materials can find applications in automotive applications and thus can help in designing fuel efficient automobiles.
Graphene is excellent material that is strong enough and it can add functionality to polymers and at the same time graphene oxide has semiconducting characteristics as well. Researchers are of the view of designing the new material that have controlled semiconducting properties that can find applications in solar cells. Researchers are also hopeful that many more application areas can be explored and the material can be designed accordingly.
Storage devices are being used for storing various types of information and new compact devices are being demanded by the industries for various applications. Now, researchers have moved forward by developing a new nano-sized magnet that can help in developing new electronic devices with improved processing features.
Research team led by Dr Will Branford of Imperial College London has found that the honeycomb pattern nano sized magnets in spin ice are superior to conventional magnetic domains as here interactions between domain is minimized. The research team has also found that the large arrays of these nano-sized magnets can be used for storing computable information.
The research team investigated the magnetic state of the nano-structured spin ices using a magnetic field and predicted the state by measuring electrical resistance and found that at temperature below minus 223C, these magnetic bits arrange themselves into patterns. This behavior changes the resistance to an electric current and the characteristics change can be identified.
Prostate Cancer Foundation (PCF) has funded a study to carry out the use of nanotechnology for drug delivery and researchers at David H. Koch Institute for Integrative Cancer Research, MIT in Phase 1 clinical trial of has used the first nanomedicine BIND 014 successfully for directly delivering the drug to the cancer cells. The research results have recently been published in Science Translational Medicine.
BIND Biosciences developed BIND 014, which is a nanomedicine that combines a ligands and nanoparticle Â and this nanomedicine contains the proven cancer medicine docetaxel encapsulated by FDA approved and biodegradable polymers. Ocetaxel has successfully been used in treating a large numbers of cancer cells including breast cancer cells, lung cancer cells and prostate cancer cells.
The nanomedicine BIND 014 is designed to target prostate specific membrane antigen (PSMA). The nanomedcine was designed to over-deliver the medicine at the tumor cell and the increased availability of the drug at the cancer cell translates significant improvement in anti-tumor activity. Although BIND 014 are being used for over a decade now for targeting PSMA but the current study also established that PSMA is also found on the surfaces of new blood vessels of other cancers.
New and improved computing devices such as high capacity storage devices are being demanded by the consumers and in line to meet the market demands, researchers have moved a step forward and found that by using nano-sized magnets, the new electronics devices with greater capacity can be made. The research findings have recently been published in the journal Science.
Although there are hard storage devices available presently and these are made up of magnetic ingredients and therefore the major problems associated with these hard discs is that the magnetic domain interact with the surrounding. The researcher at Imperial College of London has come up with a honeycomb pattern of nano-sized magnets and reduces the interference of the neighbors up to two thirds.
Researchers are working with the magnets at a temperature below minus 223 0C and are able to perform read and write operations, however still the challenge is to perform calculations and make these operational at room temperature. Researchers are studying to manipulate the magnetic state of the nano-structured spin ices using magnetic field. The researcher team led by Dr Will Branford is also looking to read their state by measuring the electrical resistance.
If we compare the current technology to the research team findings, we can clearly see that in the current technology one bit of information is stored in one magnetic domain, however the new research suggests that the cluster of multiple domains could be used to solve the complex problems in single calculations.
These are the beginnings and instead a small step forward, however there are lot of hurdles and researchers will need to overcome these before they create prototype based on the technique. Further the aspect of temperature and especially the incorporation of room temperature in the algorithm will require detailed study , however the researchers are hopeful with this new technology and hope that the honeycomb technique will be available within next 10-15 years from now.
Posted in ComputingTop Of Page |
Slow healing wounds affect large number of elderly people especially who suffers from diabetes, immune suppression and peripheral vascular disease. Slow healing or non-healing wounds often decrease the quality life in older men and women and in US alone more than 2.5 million people are affected with the problem.
Nitric Oxide has been found to critically influence the wound healing role and attempts have been made to administer Nitric Oxide (NO) around the wound areas.
Actually NO heals the wound through a complex process, which involves antimicrobial properties, modulation of platelets and vasodilatory effects, promotion of angiogenesis and administered NO has shown some goof effects, however the current administration process are not human friendly and at the same time, these are costly as well.
In a recent online issue of 6th March 2012 of Nanomedicine: Nanotechnology, Biology and Medicine, researchers from Albert Einstein College of Medicine claim that they have found a better solution for NO storage that can be used for treating slow healing wounds. Adam Freidman and his team has found that a nanoparticle platform compised of silane based sol-gel and sugar derived glasses can generate, store and deliver NO in a controlled and sustained manner and the research team has already utilized the technique in immuno-deficient mice.Â
Researchers from South Korea and Case Western University has recently reported a technique for mass production of graphene nanosheets and the research findings has been published in the online issue of the Proceedings of the National Academy of Sciences. Graphene sheets has many advantages and one of the most important properties of the sheets is that these are very good conductor of electricity.
Researchers used a unique combination of graphite and frozen carbon di-oxide in the ball miller, a canister filled with stainless steel balls and once the canister was turned for two days , the mechanical force produced graphite flakes. These graphite flakes were actually carboxylated by carboxylic acid formed during milling and were open up for chemical interaction.
The advantage of the carboxylated edges was that these graphene flakes seperates out in five or fewer layer graphene sheets once these dispersed in the solvents. Both protic and aprotic solvents were used by the researchers and found that the edges make it possible to get the end product as graphene nanosheets. Â These were further compressed into pallets and it was found by researchers that these are much better conductors of electricity.
Graphene is one of the fast growing areas where a number of researchers are exploring the possible applications of it in different fields and in continuation to various studies now researchers at University of Delaware have conducted high performance computer modeling indicating its use for DNA sequencing. The research findings have been published in the recent issue of Nano Letters.
As it is well known now that graphene is a two-dmensional sheets of carbon atoms, which are arranged in honeycomb pattern and earlier studies by researchers at University of Pennsylvania has already demonstrated that nanopores can be sculpt in the graphene sheet using an electron beam. The new approach developed by researchers now is based on the use of these nanopores in the graphene sheet.
Now the researchers propose that the DNA is allowed to pass through a few nanometer diameter hole in graphene sheetÂ and electric current flowing transversely through the graphene or current of ions flowing vertically through the pore are used for detecting the DNA bases within nanopore. The researchers are hopeful that the technique will be ultra fast and as well cost effective.
Researchers at Â NIST (National Institute of Standards and Technology) have found that the electrolytic layer thicknessÂ can significantly affect the performance of the lithium-ion battery and the researchers have built a number of nanowire batteries .Â The research findings have recently published in the journal Nano Letters.
Micro Electro Mechanical Machines (MEMS) have been emerged as the revolutionary substances that can play a key role in wide range of applications and thinner batteries with improved performance can significantly enhance the development of these MEMS, which can be as small as few micrometers. The MEMS requires fast charging battery to be used as power source and smaller the battery, smaller will be the MEMS devices.
Research team at NIST have now created a veritable forest of tiny solid state lithium ion batteries and these batteries are around 7 micrometer in height and around 800 nanometer in width made from the silicon nanowire by depositing metal layers that works as cathode in these miniature batteries. Researchers used TEM (transmission electron microscope) to study the current flow through the batteries.
CFN (centre of Functional Nanostructures) at Karlsruhe Institute of Technology is going to organize summer school events 2012. he dates for the two summer events has been announced and these will be held on nano-photonics during September 10-13, 201 and Nano-energy during SeptemberÂ 14-17, 2012.
Nano-photonics and nano-energy are the two major areas of research at CFN and these programs are designed to address the gap areas and advices required for advanced graduate students, researchers, postdocs and other scientists working in these areas. These programs provide the opportunity to interact with other students and presenting your interest in the form of a poster, which will be displayed during the entire program.
The poster should be a size of 841 X 1189 square mm in portrait form in which each participant should describe his or her research activities, scientific background and current research project an a small photograph at one corner of the poster will help identifying the poster owner and this will help in interacting common research interest.
A provision for ECTS credit point is also available and if you attend the program and present a poster, a certificate equivalent to 2 ECTS credit points will be issued. For further details you can contact to the organizers and seek further clarifications if required.
A strong hope for new types of material and devices emerged recently as researchers at Stanford University and U. S. Department of Energyâ€™s SLAC National Accelerator Laboratory has created a system of designer electrons. Â With the help of these, researchers are hopeful that they can now tune the fundamental properties of electrons.
Researchers have recently reported their findings on the journal Nature and claims that inspired by graphene, they have hand crafted, honey-comb shaped structures. Researchers initially found that electrons in this shape have graphene like properties; however researchers were able to tune these properties in electrons that were difficult in real graphene.
Researchers use Scanning Tunneling Microscope for designing the structure and with the help of STM, placed individual carbon monoxide molecules on the perfectly smooth copper surface. Placing carbon monoxide layer on the surface, the free flowing electrons were repelled by the carbon monoxide , which allowed free electrons to make honeycomb pattern. Further repositioning the carbon monoxide layer on surface changed the symmetry of electron flow and different electron patterns were achieved.
Ne3LS Network (Network on ethical, environmental, economic and legal and social issues pertaining to nanotechnology) is organizing first International conference with the theme â€œThe Responsible Development of Nanotechnology: Challenges and Perspectivesâ€.Â The conference will held at Montreal, Canada during November 1-2, 2012.
The conference will provide opportunity to interact among various nanotechnology players as well as users of the nanotechnology and some of the key issues to be deliberated during the conference includes
Â·Â Â Â Â Â Â Â Â The risk associated with the nanotechnology for social, environmental and economical and how to assess them
Â·Â Â Â Â Â Â Â Â Impacts of health care systems especially of nanomedicine
Â·Â Â Â Â Â Â Â Â The responsibility of industry , government,Â researchers and general public in the development of nanotechnology and as well as the role of industry in the development of regulations and standards
Â·Â Â Â Â Â Â Â Â The methods to consult and inform general public the issues related to nanotechnology
A lot of invited speakers from government, industry, academia and research institutions are expected to deliberate the above points in general discussion during the conference. The organizers of the conference are now seeking abstracts from various researchers across the globe in the frontier areas of nanotechnology Toxicity, nanofoods, ethics, safety and risks, regulatory standards, public private risk sharing etc. If you are a research scholar in the nanotechnology, it is the best opportunity to interact with the global fraternities. For more details, you can check the website Ne3LOS.ca.
Posted in EventsTop Of Page |
Recently Minister for Innovation, Australia Louise Asher along with Jan den Hollander, Vice Chancellor, Deakin University andÂ Dr. R.K. Pachauri, DG TERI inaugurated the TERI-Deakin Nanobiotechnology Research Centre.Â This new state of the art research centre will provide solutions for advanced research in the areas of agricultural, biomedical and allied subjects.
The honorable minister for Innovation, Services and Small Business, Louise Asher is hopeful that the new facilities will enhance the research in the areas of Nano Biotechnology, and the facilities will also provide the solutions for sustainable futures. On the occasion, Dr. R. K. Pachauri has also stressed that the new research in the area of biotechnology will help in making difference in the livings of many people.
DIRI ( Deakin India Research Initiative) was launched by the Deakin University in the year 2009 and these research initiatives were aimed at focusing research in the areas of material science, nanotechnology and biotechnology.Â These programs were taken by the university to bridge the gap between industry and academia and a number of research scholars undertake research in these frontier areas under the Deakin University Research Initiative.
If we talk about the medical applications of nanotechnology, we might see a large number of applications including the diagnosis and treatment for cancer. The applications in this area seem to be of much importance as more and more researchers wants to save people from the killer disease cancer.
Cancer especially lungÂ Â cancer is one of the most common types of cancer among people and large number of people die every year from lung cancer alone. Diagnosis is the most important aspect of saving life from cancer and a timely diagnosis is must to achieve better results.
The timely diagnosis can provide a lot of options for the treatment including the chemotherapy, radiotherapy etc., and nanotechnology is found to have great influence in treating patients in chemotherapy. A lot of nano-technique devices are being developed across the globe and these techniques are being examined as carrier of the drug for drectly delivering the drug to the cancer cells.
Researchers at Rice University and the University of Texas have found that the carbon nanoparticles based drug therapy in combination with radiation therapy can bring in more fruitful results for patients suffering from head and neck cancer. The research paper by the team has recently been published in the journal ACS Nano.
Chemotherapy is one of the techniques of cancer treatment and in the present study researchers used nanoparticles for encapsulating drug molecules and delivering the drug molecules directly to cancer cells. The researcher team James Tour and Jeffrey Myers combined paclitaxel (PTX) and Cetuximab (Cet) with functionalized polyethylene glycol hydrophilic carbon clusters.
Paclitaxel (PTX) is used in chemotherapy for treating head and neck, lung, ovarianand breast cancers and the researchers have developed a new way to combine PTX with Cetuximab, with carbon clusters that absorb the active ingredient and the new compound is water soluble and at the same time is much more effective in targeting tumors. While treating with this technique researchers also observed that much smaller dosages is required here by eliminating the Cremophor , which is used in conventional treatments and therefore it is the real advantage of the new technique.
Engineered nanoparticles are being used for various applications and billions of these nanoparticles are now part of our daily food. Researchers have now studied a particular FDA approved nanoparticle and found that it may be harmful to human health.
The research led by Michael Shuler, Professor of Chemical Engineering, Cornell University on a FDA approved polystyrene nanoparticle, which is commonly found in various food items and vitamins and the research findings has been published in the online journal Nature Nanotechnology. The study reveals that the short time exposure of the nanoparticles initially blocks iron absorption, which is an essential nutrients required for our body.
The researchers took chicken and human cells in Petri dishes and exposed the cells with short range and long range with nanoparticles. In both the cases they got similar results and in short range the blockage of iron absorption was notices, however long range exposure caused change in intestinal cell structure.
The research has opened the debate on the safety of these nanoparticles, which were earlier considered quite safe, however the results indicate otherwise and therefore a complete study on the nanoparticles and especially food nanoparticles is required.
Posted in Society & EthicsTop Of Page |
Arrogene, a fast growing company thatÂ was formed in the year 2007 for commercializing the new cancer targeting drugs. The company uses a proprietary molecular delivery platform and it develops the latest and new generation nano-polymers based therapeutic and diagnostic drugs.
WestPark Capital Inc., a full service investment bank, has now announced a second offering of private placement for Arrogene Nanotechnology Inc for a total of 610,000 units. These units consists one share of common stock and two common stock purchase warrants and generated $ 610,000. It is already understood that the earlier closing of January 2012 generated $500,000 and thus totaling a gross of $1,100,000.
The offerings were made only by the private placement memorandum and the amount received will be used as working capital and various other purposes such as research and development including in the areas of brain, breast and lung cancer.Â WestPark Capital acted as a placement agent and it also provides various services especially in emerging growth sectors.
Water is an essential ingredient that is required by each human for consumption and in todayâ€™s scenario more than 600 millions people across the globe have either scarcity of water or are living under water stressed conditions and it is estimated that by 2025, the number will be 4 -5 times of current level.
People has already used nanotechnology or nanomaterials for making the water potable from seawater by desalination and demineralization, however the techniques are still not fully commercialized or are very costly and therefore researchers across the globe are looking for alternative techniques that can be cost effective. Reverse osmosis is one of the widely used technologies today; however its disadvantages include the huge power consumption required for operating the process at very high pressure.
Researchers at the Centre for Electrochemical Sciences in Germany has now demonstrated the desalination battery that can be operated by performing cycles in reverse and the battery captures and releases the sodium chloride, which is the main constituents in sea water. Although the researchers state that their research is at preliminary stage, however they are successfully able to demonstrate that the battery captures salt from one seawater stream and releases it into another seawater stream.
The report findings has been published in the Nano Letters of Jan 23, 2012 issue and researchers claim that the battery will consume less power, and the water produced can be used for various purposes including irrigation, industrial applications etc.
Titanium is one of the metals, which on active state act as catalyst for splitting water and converting it into the constituentâ€™s hydrogen and oxygen. The fine surfaces Â of the metal in active state is actually responsible for the conversion, however the bulk of the metal remains inert and researchers are now claims that they have developed an alternate similar in structure and chemical activity that is cost effective and can possibly replace titanium.
Researchers from Berkeley National Laboratory synthesized a molecule that has triangular shape MoS2 units along the edges of molybdenite crystals. The bulk of the molybdenite crystalline material being inert and only has the catalytic activity edges that perfectly resembles with the metal catalyst. These can be used to make new materials that are much more efficient and cost effective.
The lead researchers Christopher J. Chang and Jeffrey R. Long are the lead authors and the research paper has been published in the online journal Science. Molybdenite is the crystalline sulfide of molybdenum and although MoS2 is commonly used in various lubricant formulations, molybdenite is standard catalyst used to remove sulphur from petroleum and natural gas. Molybdenite in nanoparticle form has been demonstrated as catalyst by various researchers in recent past and it seems to be a good choice as catalyst for electrochemical and photochemical generation of hydrogen from water.
Grapheneâ€™s importance has been reported for its unique properties and it is one of the most researched materials that can suitably replace computer chips, however the major drawback seems to be too much leakage of electric current once it is packed densely and this might cause the chip to melt down.
Graphene exists in single layer of carbon and a large number of researchers are working to find solution for the problem as mentioned above so that it can be satisfactorily used in a computer chips. A team Of Manchester Scientists led by Nobel Laureates Prof Konstantin Novoselov and Prof. Andre Geim have now opened a third dimension, which can really solve the problem.
Researchers in the previous studies have used grapheme in horizontal directions and now the Manchester University research findings has been published in a recent issue of Science, where researchers have suggested graphene to be used in vertical direction instead of horizontal direction.
The researchers obtained a tunneling diode by using graphene in electrode form and through electronic tunneling via dielectric into another metal. Researchers thus got a vertical field effect tunneling transistor that contains the special ingredient graphene.
Solar energy is one of the readily available energy source and the major problem associated with the tapping of this renewable energy is that at present it is costly than the conventional sources of energy such as coal, oil and gas. Researchers are working hard to minimize the cost by either bringing down the solar panel cost or enhancing the efficiency of the solar panels.
A lot of research is taking in the direction of organic solar cells which will not only help in making these with cost effective substrate such as plastics but will have high potential to improve the efficiency of the solar panels. The challenge with the solar cells technology or specifically the organic solar cell technology is the minimizing the overall cost of production and suitable technique so these are manufactured at industrial scale.
Polyera, has a vast experience in the area of opto-electronics and functional electronics and it has recently claimed that the leading supplier of high performance functional materials has achieved a record 9.1% efficient polymer/fullerene organic solar cells. The company claims to have achieved this using its proprietary semiconductor material Activink PV 2000. The additional feature of the newly developed technology is itâ€™s commercial viability and the company has plan of commercialization.
Hard disks are one of the common storage devices that uses granular media, a nano magnetic grains that are randomly arranged on the disks and each disks contains a number of such grains. The common approach to increase the storage capacity can either be achieved by reducing the grain size or reduce the number of grains per bit, however both the approaches have limitations and it is really difficult to go beyond a particular grain size.
Researchers are working hard to push beyond the terabit per square inch limit, which researchers seem to cross a little bit difficult. Now researchers at the Institute of Material Research and Engineering at A*STAR and other institutes has suggested a new alternative approach to enhance the storage devices and they called it as BMP (bit-patterned media) and the research findings has been published in the journal Nanotechnology
Researchers claim that they were able to fabricate BMP at densities as high as 3.3 terabits per square inch using a combination of technologies and researchers found that the BMP technology holds promises to recording densities in excess of 1.5 terabits per square inch. Researchers first used electron beam lithography followed by the deposition of cobalt- palladium films by magnetic film deposition technique on the nanospots obtained by lithography.
Gel is a typical structure that holds the liquid within its cavities and researchers led by Jie Cai now claims that they have made a novel nanocomposite that consists of almost air. The research findings have been published in a recent issue of the journal Angewandte Chemie.
An aerogel holds air and specifically if we see an example of the silicon oxide, the aerogel of which consists more than 99% weight air and thatâ€™s why these aerogel are light weight comparable to the weight of air and are translucent similar to solidified smoke. One of the characteristics of these aerogels is that these are non-inflammable and are good insulators.
Researchers have developed a nano- composite of cellulose and silicon. The process involves in two steps and in first step, researchers produced cellulose gel from alkaline urea solution by dissolving and regenerating it in the form of nanofibrillar, which acts as scaffold for silica gel and in second step they produced silica gel by standard sol-gel process and the composite gel was obtained by drying the liquid.
The newly developed aerogel was tested for various physico-chemical properties and it demonstrated many properties superior to the conventional products. This new product can find applications in various areas including insulation in space shuttles.