Carbon Nanotube used for detecting cancer
29 November 2008Researchers at Stanford University have developed a new coating for single wall carbon nanotubes that can attach a number of different targeting agents to the surface of the nanotube. This coating is specially made biocompatible and it is developed from polyethylene glycol (PEG). The research finding has been published in the Journal Nature Biotechnology.
Conventionally the fluorescent tags are used for detection of cancer related proteins and researchers found that Bright Raman Optical Tags are not only easily detected but when irradiated with light, these carbon nanotube assay are at least 1000 times more sensitive than the fluorescent tags. Further researchers used a varying concentration of 1 femtomoles to 10 nanomoles and found that Raman tags are useful in detecting biomolecules over this wide range.
Dr. Hongjie Die of Stanford University and the Center of Cancer Nanotechnology Excellence led the research and the detailed paper, “Protein Microarrays with carbon nanotubes as Molecular Raman labels” was appeared in the Journal. The above research was supported by NCI Alliance for Nanotechnology in cancer.
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