Drug release through Nano bubble

3 June 2007

Stents are the medical devices or medical implants used for various medical purposes including preventing accumulation of cholesterol in arteries. These devices therefore are necessary for certain patients suffering from heart related problems and with the use of these implants, surgeries in certain cases can be prevented. The major problem with these stents is that their biocompatibility.

Stents or vascular stents are generally made up off metal or plastic material and it acts as a small tube that reinforces the wall of specific organ if implanted there in the specific organ. Since their use, the compatibility of stents with human tissues in nearly one third patients reacts to it causing shut down of the vassel.

During the last two decades, the coated vascular stents were developed. After coating the stents with differents substances it was expected that these stents will bring down the rejections. More and more coated stents were produced and used especially for treating coronary heart disease. Sometimes drug releasing stents are most important for treating diabetes and till now these coated vascular stents are being used for various purposes.

The Forschungszentrum Dressler- Rossendorf (FZD) developed a new nano-porous stent that have millions of nano bubbles under the surface of stent. These stents are superior than the conventional stents as through these stents the drug is released slowly and over a long period and particularly at the desired wall. Various manufacturers and marketers are looking for these types of stents so that the rejection of stents is prevented.

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