Nanotechnology helps in reducing staph infection
1 May 2009Staph infections are generally caused by staphylococcus aureus bacteria and sometimes the infections can be more severe especially if the bacteria finds it’s way to bloodstream, urinary tract or heart/lungs. The bacteria is becoming more and more resistant to the available common antibiotics and therefore the use of nanotechnology as suggested by the Scientists of Albert Einstein College of Medicine of Yeshiva University can be very much beneficial for curtailing the staph infection.
The father son duo at Einstein, Dr. Joel M. Friedman and Adam Friedman has developed a new nanotechnology based drug delivery system that shows promise to fight the staph infections more quickly and effectively. The nanoparicles used for the current study were capable to carry out payloads of the drugs and release the drugs at the sites in a controlled manner. The drug used for the study was nitrous oxide, which can significantly heal the site and kill bacteria or enhance the blood circulation.
As the life of nitrous oxide is very short and its delivery to targeted tissues was also not fruitful during earlier studies, the nitrous oxide used for present study for killing bacteria was generated within the nanoparticle. The nanoparticles were designed in such a way so that nitrous oxide is produced from sodium nitrite and it is released at desired site in a controlled manner.
The trials of the technique has already been conducted on mice infected with methicillin resistant staph or MRSA and it was found that after a week there were significant improvement in the mice in comparison to the other group which was not treated with nitrous oxide. The research group at Einstein now plans to have a full fledged clinical trial against MRSA and other infections and scientists are hopeful to have a better and quick solution to fight staph infections.
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sir am Vivek Senapati, MSc Applied Microbiology, VIT University, very much interested in nanotechnology and also doing my 6 months project work on this and i want to continue in this line. Sir if possible can you please guide or help me in this aspect.