Nanotechnology in cancer treatment
7 April 2008Researchers at Washington University School of Medicine in St Louis used nanotechnology for delivering drug directly to tumors. Researchers used drug coated nanoparticles and found that a drug dose 1000 times lower is effective in slowing down tumor growth in rabbits. The reduced dosage of drugs will definitely benefit millions of cancer pateints as many of the chemotherapeutic drugs have unwanted side effects.
Researchers published their finding in The FASEB online journal and claimed that significant reduction in tumor growth in rabbit was noticed after treating with fumagillin. Fumagillin in combination with other anticancer drug is affective in reducing tumor growth. Fumagillin released to the cells of growing blood vessels and it quickly blocks multiplication of blood vessel cells and it slows down tumor growth by cutting the blood supply to cancer cells.
Fumagillin can have neurotoxic side effects in humans and also high doses of fumagillin is required if given by conventional standard methods. A low concentration of fumagillin nanoparticles is found effective and at the same time fumagillin nanoparticles shown no adverse neurotoxic side effects in rabbits.
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