New Photoluminescent Nanoparticles Glow Through Thick Layer of Tissues

29 September 2012

Optical bioimaging is emerging very fast and it is one of the promising tools being explored in the biomedical applications, however current technologies limit the ability to look deeper inside. Due to non-availability of high resolution and high contract imaging tools, a group of international researchers and scientists worked together for developing a robust and high resolution optical device that can help them in identifying tumors.

The group of researchers has created a unique photoluminescent nanoparticles that are able to pass light through a depth of more than 3 centimeters and actually these nanoparticles are inside a shell of calcium fluoride and the nanocrystalline core contains thulium, sodium, fluorine and ytterbium. The use of calcium fluoride shell minimizes the possible side effects as it is commonly found in our bones.

These nanoparticles as mentioned above have different behavior towards light, as these nanoparticles absorb infrared light and emit infrared light of lower wavelength than the absorbed light and this is completely deferent than the normal pattern of absorbing and emitting lights of biological tissues and therefore these nanoparticles can suitably be used for obtaining deeper and higher contrast images.

The research paper has been published on 28th August in the online issue of ACS Nano Journal. The research teams of various institutes and research centre from US, China, South Korea and Sweden have worked together. Distinguished Scientists Paras N Prasad, Professor and Executive Director, UB’s Institute of Lasers, Photonics and Biophotonics & Gang Han, Assistant Professor, University of Massachusetts Medical College has jointly led this research study.

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2 Responses to “New Photoluminescent Nanoparticles Glow Through Thick Layer of Tissues”

  1. Deep-tissue optical bioimaging: Photoluminescent Nanoparticles glow through thick layer of tissue – The Global Innovations Says:

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