Bionanotechnology in diagnosis of infectious agents
9 June 2007One of the possible applications of bionanotechnology is timely diagnosis of various diseases. Many infectious agents such as SARS, dengue, Asian flue etc spread out very fast and cause epidemic outbreaks with a very high death rate. Therefore there is a great potential to use nanotechnology for diagnosing infectious agents.
Using nanolithography, antibodies could be localized in an exact place or spot, however nonspecific background binding of the proteins and detection sensitivity is the major problem associated with this technique. Nanotechnology therefore helps in providing the technique that is capable to identify and detect a single viral particle. The high sensitivity is needed as even a very few 5-10 viral particles of HIV can infect the other person.
It is also necessary to identify the antibodies quickly as some of these infectious agents are quite stable as well as some of the infectious agents are aggressive and these could be easily transmitted in trace amounts. Some of the infectious agents such as prions and infectious amyloidoses could be transmitted on fento molar concentration level. Therefore, diagnosis capable to identify and diagnose these infectious agents is extremely important and bionanotechnology helps us in early diagnosis of these infectious agents.
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