Nanodevice using DNA building blocks Developed
31 May 2012DNA Nanotechnology a new emerging field where researchers across the globe are working to explore the use of a nanomaterial that builds tiny programmable structures for various applications. Now, one of the research team at Wyss Institute for Biologically Inspired Engineering, Harvard University has come up with a new method for building complex nanostructures using short synthetic strands of DNA.
The research was conducted under the guidance of Dr. Peng Yin, Faculty Member Wyss Institute and Assisstant Professor of Systems Biology, Harvard University and the research findings has been published in the recent issue of the journal Nature.
The specific synthetic strands of DNA known as single stranded tiles (SSTs) can be programmed in such a way so that these assemble themselves in specific shapes. Each SST, a single short strand of DNA interlocks with another tile if it has complementary sequence and if it has no complementary sequence, it will not combine with the other tile. Thus the tile having complementary sequence combines or assembles in predetermined shapes.
Researchers carried out a number of experiments where they have created hundreds of designs including numbers, fonts and even Chinese characters and used hundreds of tiles for single structures of 100 nanometers. Researchers are hopeful to design the SSTs that can have very useful applications in medicine and allied science disciplines and as these are totally synthetic, these can be made biocompatible as well.
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