Nanoparticle developed for protecting antioxidants

1 September 2008

Dr. Ken Ng and Dr Ian Larson of Monash University’s faculty of Pharmacy and Pharmaceutical sciences have developed a nanoparticle that is found useful in protecting antioxidants and thus helpful in absorbing it in digestive system of human being. Antioxidants are essentially required by each human being for protecting ourselves from free radicals, which are continuously generated in our body.

In a general healthy person, antioxidants from diet itself are sufficient, however for high risk persons additional sources of antioxidants are required. Researchers found that these additional antioxidants given orally are decomposed and destroyed by acids and enzymes of our digestive system and only a very small percentage is absorbed in the body.

Researchers at Monash University developed a Chitosan ( a natural substance from crab shell) biopolymeric nanoparticle, which acts as a carrier for antioxidants. The antioxidants get delivered to the small intestine safely in the Trojan horse. In the small intestine, the nanoparticle attach themselves to the intestinal walls and thus allowing antioxidants to leak into the intestinal cell and which later absorbs in the blood stream.

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