Nanopore that can separate small molecules developed

13 March 2008

Thayumanvan and his students at UMass Amherest, Department of Chemistry have developed a method for fabricating special nanopores that can separate small molecules including proteins. Researchers selected a membrane containing nanopore and immersed it in a tin solution. Tin ions have positive charge and therefore these positive ions attached to the inner side of the nanopores.

Upon filtering a negatively charged polymer solutions through the nanopore mambrane, these positive charged tin ions attract negatively charged molecules and these molecules further react with the desired molecules within the limited space inside nanopores. The advantage of this method over conventional method is that in this method you can control nanopore size as well as it is less time consuming and you get uniform layer inside nanopores.

These nanopores can find applications in many diverse areas including fuel cell membrane, DNA sequencing and other diagnostic medical tests. These nanopores are also suitable for sensor applications, as even a single charged molecule inside nanopore can produce measurable electric current. Researchers carried out experiments with different type of polymers and have created nanopores of various sizes and observed that molecules based on their sizes can efficiently separated through these nanopores.

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